| Product Name: |
Octyl gallate |
| Synonyms: |
3,4,5-trihydroxy-benzoicacioctylester;n-octylesterof3,4,5-trihydroxybenzoicacid;oktylesterkyselinygallove;N-OCTYL GALLATE;OCTYL 3,4,5-TRIHYDROXYBENZOATE;OCTYL GALLATE;GALLIC ACID OCTYL ESTER;GALLIC ACID N-OCTYL ESTER |
| CAS: |
1034-01-1 |
| MF: |
C15H22O5 |
| MW: |
282.33 |
| EINECS: |
213-853-0 |
| Product Categories: |
Aromatic Esters |
| Mol File: |
1034-01-1.mol |
| |
Factory supply antioxidant Octyl gallate 1034-01-1
White or milky powder, odorless, almost insoluble in water, soluble in methanol, soluble in acetone, ethanol, ether and propane-1,2-diol, slightly soluble in peanut oil and chloroform. Used as antioxidant.
Function of Octyl gallate
1. Acts as an antioxidant and helps to protect our cells against oxidative damage.
2. Have anti-fungal and anti-viral properties.
3. Was found to show cytotoxicity against cancer cells, without harming healthy cells.
4. Used as a remote astringent in cases of internal haemorrhage.
5. Used to treat albuminuria and diabetes. Some ointment to treat psoriasis and external Haemorrhoids contain gallic acid
| Octyl gallate Basic information |
| Description References |
| Product Name: |
Octyl gallate |
| Synonyms: |
Progallin O;3,4,5-Trihydroxybenzoic acid octyl ester;Gallic acid octyl;Stabilizer GA-8;3,4,5-trihydroxy-benzoicacioctylester;OCTYL 3,4,5-TRIHYDROXYBENZOATE FOR SYNTH;n-octylesterof3,4,5-trihydroxybenzoicacid;oktylesterkyselinygallove |
| CAS: |
1034-01-1 |
| MF: |
C15H22O5 |
| MW: |
282.33 |
| EINECS: |
213-853-0 |
| Product Categories: |
Aromatic Esters |
| Mol File: |
1034-01-1.mol |
| |
| |
| Octyl gallate Chemical Properties |
| Melting point |
101-104 °C(lit.) |
| Boiling point |
262.5°C (estimate) |
| density |
1.0984 (rough estimate) |
| refractive index |
1.6200 (estimate) |
| storage temp. |
0-6°C |
| solubility |
soluble2.5%, clear, colorless (AcOH (MEOH)) |
| pka |
7.94±0.25(Predicted) |
| form |
neat |
| Water Solubility |
20mg/L(29.99 ºC) |
| BRN |
2132305 |
| CAS DataBase Reference |
1034-01-1(CAS DataBase Reference) |
| EPA Substance Registry System |
Benzoic acid, 3,4,5-trihydroxy-, octyl ester (1034-01-1) |
| Hazard Codes |
Xn |
| Risk Statements |
22-43 |
| Safety Statements |
24-37 |
| WGK Germany |
1 |
| RTECS |
LW8225000 |
| TSCA |
Yes |
| HS Code |
2918 29 00 |
| Toxicity |
LD50 orally in Rabbit: 1960 mg/kg |
| Provider |
Language |
| Octyl gallate |
English |
| SigmaAldrich |
English |
| |
| Octyl gallate Usage And Synthesis |
| Description |
Octyl gallate is the ester formed by 1-octanol and gallic acid. It can be used as an antioxidant and preservative to be supplemented to the food. It has been demonstrated to be an effective fungicide being capable of inhibiting the growth of S. cerevisiae and Z. bailii as it can inhibit the fluidity of the cell membrane through acting as a nonionic surface-active agent. It is also capable of killing both DNA and RNA viruses with a relatively moderate cytotoxicity. For example, it has the potential to treat influenza. Octyl gallate also has certain bactericidal activity, being capable of treating the infections associated with enterococci. |
| References |
[1]Ken-Ichi, Fujita, and K. Isao. "Antifungal activity of octyl gallate. " International Journal of Food Microbiology 79.3(2002):1
[2]Gutiérrez-Fernández, J, et al. "Antimicrobial activity of binary combinations of natural and synthetic phenolic antioxidants against Enterococcus faecalis. " Journal of Dairy Science 96.8(2013):4912-20.93.
[3] Yamasaki, H, et al. "Antiviral effect of octyl gallate against influenza and other RNA viruses. " International Journal of Molecular Medicine 19.4(2007): 685-688. |
| Description |
During the 1940s, propyl gallate and several other alkyl gallates were allowed for use in foods in a number of countries. Since gallic acid contains three phenolic hydroxyl groups, it is a rather potent antioxidant; however, the propyl ester has a significant degree of water solubility. As a consequence, propyl gallate tends to partition into any water phase which may be present and to complex with iron salts to give bluish black colors. Also, its relatively poor resistance to heat degradation makes it ineffective for baking and frying applications. The higher alkyl gallates (butyl and octyl) are more fat soluble. |
| Chemical Properties |
White powder |
| Uses |
Used in treatment of alcohol dependence. |
| Uses |
Octyl gallate is an antioxidant that is used as a preservation agent in a wide variety of foods, oils, and cosmetics. |
| Definition |
ChEBI: A gallate ester obtained by condensation of the carboxy group of gallic acid with the hydroxy group of octanol. |
| Contact allergens |
Octyl gallate, a gallate ester (E 311), is an antioxidant added to food and cosmetics to prevent oxidation of unsaturated fatty acids. Cases were sparsely reported in food industry or from lipsticks. Patch tests are frequently irritant. |
| Safety Profile |
A poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating fumes. |
Hunan JK International Trade Corporation / JK BIO-CHEM CO.,LTD is a professional exporter of food/feed additives and food /feed ingredients in China. With years of development, now we are able to provide the following food additives and food ingredients: thickeners, antioxidants, preservatives, vitamins, sweeteners, proteins, acidulants, nutritional supplements, flavours, coenzyme and so on.
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