. Introduction
Choline (commonly in the form of Choline chloride) is one of the B categories of vitamin. It is acetylcholine in the biological organization. It is the components of lecithin and nerve acid fat. It is used by most animals as a precursor of acetyl choline, which influences the transmission of impulses from nerves to muscles. It is also used as a source of methyl groups. In feed, the content of natural choline chloride is limited. It can not satisfy complete demand for the animal growing. Therefore, choline chloride is widely used as feed additive at home and abroad. It will stimulate the animal or poultry's growth, put on their weight rapidly and boost up the body's immunity function. It has prominence effects on improving the quality and quantity of eggs and meat. On the contrary, shortage of choline may cause liver diseases, retarded growth, perosis, reduced egg-laying rate and increased mortality.
2. Form: Choline Chloride 50%, 60 %( powder form); Choline Chloride 70%, 75 %( liquid form) and Choline Chloride 98 %( crystalloid form)
Test Method: Renei Salt Test, AgNO3 Test, etc.
| choline chloride content |
≥60.0% |
| tma residue |
≤300ppm |
| loss on drying |
≤2.0% |
| thinness (through 20mesh) |
≥95% |
| Choline chloride Basic information |
| B vitamins Content Analysis Toxicity Limited use Chemical Properties Uses Production method |
| Product Name: |
Choline chloride |
| Synonyms: |
Acetylcholine Chloride Ep Impurity A(c;Choline Chloride, Animal-Free;(2-hydroxyethyl)trimethyl-ammoniuchloride;(beta-Hydroxyethyl)trimethylammonium chloride;(beta-hydroxyethyl)trimethylammoniumchloride;2-hydroxy-n,n,n-trimethyl-ethanaminiuchloride;Ammonium, (2-hydroxyethyl)trimethyl-, chloride;Bilineurin chloride |
| CAS: |
67-48-1 |
| MF: |
C5H14ClNO |
| MW: |
139.62 |
| EINECS: |
200-655-4 |
| Product Categories: |
medical;Quarternary ammonium salts;Ammonium Chlorides (Quaternary);Biochemistry;Quaternary Ammonium Compounds;Vitamin Related Compounds;TCI-;Aliphatics;Amines;LIPOTRIL;Vitamins;Antioxidants;Intermediates & Fine Chemicals;Pharmaceuticals;substrate |
| Mol File: |
67-48-1.mol |
| |
| |
| Choline chloride Chemical Properties |
| Melting point |
302-305 °C (dec.)(lit.) |
| density |
1.0238 (rough estimate) |
| FEMA |
4500 | Choline chloride (Also Includes Choline) |
| refractive index |
1.5400 (estimate) |
| storage temp. |
0-6°C |
| solubility |
H2O: 1 M, clear, colorless |
| form |
Adhering Crystals |
| color |
White |
| PH |
5.0-7.5 (25ºC, 1M in H2O) |
| Water Solubility |
soluble |
| λmax |
λ: 260 nm Amax: 0.015
λ: 280 nm Amax: 0.010 |
| Sensitive |
Hygroscopic |
| Merck |
14,2206 |
| JECFA Number |
2003 |
| BRN |
3563126 |
| Stability: |
Stable. Incompatible with strong oxidizing agents, moisture. Store under a dry atmosphere. |
| InChIKey |
SGMZJAMFUVOLNK-UHFFFAOYSA-M |
| CAS DataBase Reference |
67-48-1(CAS DataBase Reference) |
| NIST Chemistry Reference |
Choline chloride(67-48-1) |
| EPA Substance Registry System |
Choline chloride (67-48-1) |
| Hazard Codes |
Xi |
| Risk Statements |
36/37/38 |
| Safety Statements |
26-36 |
| WGK Germany |
1 |
| RTECS |
KH2975000 |
| F |
3-9 |
| TSCA |
Yes |
| HS Code |
29212900 |
| Hazardous Substances Data |
67-48-1(Hazardous Substances Data) |
| Toxicity |
LD50 in rats (g/kg): 0.400 i.p.; 6.64 orally (Hartung, Cornish) |
| Provider |
Language |
| 2-Hydroxy-N,N,N-trimethylethanaminium chloride |
English |
| SigmaAldrich |
English |
| ACROS |
English |
| ALFA |
English |
| |
| Choline chloride Usage And Synthesis |
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