1.Product Information
| ITEM |
SPECIFICATION |
RESULT |
| Identification |
Meets the requirement |
Confirm |
| Appearance |
White crystalline powder |
White crystalline powder |
| Specific optical rotation |
+13.5 ~ +15.5 |
+13.8 |
| Assay(dry basis) |
96.5_102.0% |
99.44 |
| Water |
4.5~5.5% |
5.1% |
| Reducing sugars |
0.2% max |
0.02% |
| Nickel |
1ppm max |
<1ppm |
| Lead |
0.5ppm max |
<0.5ppm |
| Sulfated ash |
0.1% max |
<0.1% |
| Total plate count |
50cfu/g max |
<10cfu/g |
| Coliform |
Negative |
Negative |
| Salmonella |
Negative |
Negative |
| Yeast & Mold |
10cfu/g max |
<10cfu/g |
| Conclusion: Complied with the standard |
1) Name:Lactitol
2) Purity: 99%
3) Cas no.:585-86-4
4) Appearance: White Powder
5) Supply Ability : 2Mt/Per Month
6) Storage: Store in a well-closed container away from moisture
| LACTITOL Basic information |
| Product Name: |
LACTITOL |
| Synonyms: |
LACTITOL;4-O-(beta-D-galacto-hexopyranosyl)-D-glucitol;4-O-?D-Galactopyranosyl-D-glucitol monohydrate;4-O-(β-Galactosyl)-D-glucitol;D-Glucitol, 4-O-.beta.-D-galactopyranosyl-;4-O-B-D-GALACTOPYRANOSYL-D-GLUCITOL MONOHYDRATE;Lactnol;4-β-D-galactopyranosyl-D-glucito1 |
| CAS: |
585-86-4 |
| MF: |
C12H24O11 |
| MW: |
344.31 |
| EINECS: |
209-566-5 |
| Product Categories: |
|
| Mol File: |
585-86-4.mol |
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| |
| LACTITOL Chemical Properties |
| Melting point |
146° |
| alpha |
D23 +14° (c = 4 in water) |
| Boiling point |
788.5±60.0 °C(Predicted) |
| density |
1.69±0.1 g/cm3(Predicted) |
| solubility |
Slightly soluble in ethanol (95%) and ether. Soluble 1 in 1.75 of water at 20°C; 1 in 1.61 at 30°C; 1 in 1.49 at 40°C; 1 in 1.39 at 50°C. |
| pka |
12.84±0.70(Predicted) |
| |
| LACTITOL Usage And Synthesis |
| Description |
Lactitol (4-o-(|3-D-Galactopyranosyl)-D-glucitol) is a disaccharide sugar alcohol derived from lactose by reduction of its glucose moiety. Lactitol has not been found in nature. It is about 0.4 times as sweet as sucrose.
In vitro studies with galactosidase-containing enzyme preparations have demonstrated that lactitol is hydrolyzed only very slowly. In incubations with human intestinal biopsies, it has been shown that the human intestinal mucosa does not exhibit any significant dis accharidase activity with lactitol as a substrate. The hydrolytic activities towards lactitol and isomalt were only 1.3% of those towards lactose and isomaltulose, respectively. Corresponding exper iments with intestinal preparations of germ-free pigs and convention ally kept minipigs gave similar results. These observations indicate that lactitol is the most slowly digested disaccharide sugar alcohol. However, in vitro investigations with intestinal enzyme prepara tions provide only relative figures on hydrolysis rates. Experiments with humans and 14C-labeled lactitol during jejunal perfusion indi cate that lactitol is virtually not assimilated by the human small intestine. After passage through the small intestine, ingested lac titol reaches the bacterially colonized segments of the gut where intensive fermentation takes place. Short-chain fatty acids (acetate, propionate, butyrate) are the major fermentation end products which are subsequently further metabolized by the host.
Lactitol is slowly fermented in growing cultures by some strepto cocci, actinomyces and lactobacilli. When fed at 25% of the diet to rats that had been inoculated with Streptococcus mutans, lactitol was about equally as cariogenic as sorbitol and significantly less cariogenic than sucrose. Test candies and chocolates sweetened by lactitol are hypoacidogenic in humans tested by plaque pH telemetry. Boiled sweets made with 100% lactitol are rough in texture owing to crystallization, and caused some gastrointestinal upsets in human volunteers. Since lactitol has only one-third the sweetness of sucrose, sweets need an additional sweetening agent for palatability. |
| Chemical Properties |
Lactitol occurs as white orthorhombic crystals. It is odorless with a sweet taste that imparts a cooling sensation. It is available in powdered form and in a range of crystal sizes. The directly compressible form is a water-granulated product of microcrystalline aggregates. |
| Production Methods |
Lactitol is produced by the catalytic hydrogenation of lactose. |
| Pharmaceutical Applications |
Lactitol is used as a noncariogenic replacement for sucrose. It is also used as a diluent in solid dosage forms.(1) A direct-compression form is available,(2,3) as is a direct-compression blend of lactose and lactitol. Lactitol is also used therapeutically in the treatment of hepatic encephalopathy and as a laxative. |
| Safety |
Lactitol is regarded as a nontoxic and nonirritant substance. It is not fermented significantly in the mouth, and is not cariogenic.It is not absorbed in the small intestine, but is broken down by microflora in the large intestine, and is metabolized independently of iulin. In large doses it has a laxative effect; therapeutically, 10-20 g daily in a single oral dose is administered for this purpose.
LD50 (mouse, oral): >23 g/kg
LD50 (rat, oral): 30 g/kg |
| storage |
Lactitol as the monohydrate is nonhygroscopic and is stable under humid conditions. It is stable to heat and does not take part in the Maillard reaction. In acidic solution, lactitol slowly hydrolyzes to sorbitol and galactose. Lactitol is very resistant to microbiological breakdown and fermentation. Store in a well-closed container. When the compound is stored in an unopened container at 25°C and 60% relative humidity, a shelf-life in excess of 3 years is appropriate. |
| Regulatory Status |
GRAS listed. Accepted for use as a food additive in Europe. Included in the Canadian List of Acceptable Non-medicinal Ingredients. |
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| LACTITOL Preparation Products And Raw materials |
Hunan JK International Trade Corporation / JK BIO-CHEM CO.,LTD is a professional exporter of food/feed additives and food /feed ingredients in China. With years of development, now we are able to provide the following food additives and food ingredients: thickeners, antioxidants, preservatives, vitamins, sweeteners, proteins, acidulants, nutritional supplements, flavours, coenzyme and so on.
Our food additives and food ingredients, especially our Ascorbic Acid (Vitamin C), Acesulfame-K, Aspartame, Citrates, Dextrose, D-Xylose, Erythorbic Acid, Fumaric Acid, Fructose,Maltodextrin, Malic Acid, Monosodium glutamate, Lactic Acid Potassium Sorbate, Sodium Erythorbate, Sodium Cyclamate, Sodium Saccharin, sodium benzoate, Sodium ascorbate, Sorbic Acid, xanthan Gum, Xylitol, Tartaric Acid, I+G, , Vanillin, Sucralose, Stevia and so on, have been exported to more than 60 countries for our good quality products.
Our staff of sales and technical support is available to help you in selecting the right protection for your application as well as to provide you with samples of our products for evaluation. At High Five, we are committed to providing the highest level of customer service, competitive pricing, speedy delivery and a comprehensive, cutting-edge product offering. Our ultimate goal is your satisfaction.
Packing&Shipping
FAQ
Q1.What's the payment terms?
We could accept T/T, L/C, DP payment terms.
Q2.How about the different index of products in same application?
Specifications can be customized according to your application.
Q3.How about the samples of products?
We can provide free samples under 2Kg(not including freight charge).
Q4.How about the price of products?
Our products are chemical synthesis got from underground brine, which is available for a variety of usage. Our products are high purity with good quality, and the price is based on different specification and quantity.
Q5.What's the shelf life for the cargoes?
Our product's shelf life is 2 years, which is based on dry and ventilated storage.
Q6.What's the package of the cargoes?
20kg/25kg woven bags, within plastic bags, or as customized.
Q7.What's the delivery time?
We usually deliver the cargoes within 10~20 days after receiving customer's payment or original L/C.
Q8.Which documents can we supply?
Commercial Invoice, Packing List, Certificate of Analysis, Certificate of Origin (FORM E), Bill of Loading, ISO etc.
The documents will be sent by Express within 24 hours against your full payment.
Q9.Why do you choose us?
We accept safe and diversified payment terms.
We supply a price trend to ensure clients know marketing information in time. We will take charge of 100% responsibility for
quality issue. We strive to create value for each customer we serve by meeting their unique needs and providing solutions to solve their problems and achieve their objectives.
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