Lactic acid is a chemical compound that plays a role in various biochemical processes and was first isolated in 1780 by the Swedish chemist Carl Wilhelm Scheele. Lactic acid is a carboxylic acid with the chemical formula C3H6O3. It has a hydroxyl group adjacent to the carboxyl group, making it an alpha hydroxy acid (AHA).
In solution, it can lose a proton from the carboxyl group, producing the lactate ion CH3CH(OH)COO. Compared to acetic acid, itspKa is 1 unit less, meaning lactic acid deprotonates ten times more easily than acetic acid does. This higher acidity is the consequence of the intramolecular hydrogen bridge between the α -hydroxyl and the carboxylate group, making the latter less capable of strongly attracting its proton.
Lactic acid is miscible with water or ethanol, and is hygroscopic.
Lactic acid is chiral and has two optical isomers. One is known as L-(+)-lactic acid or (S)-lactic acid and the other, its mirror image, is D-()-lactic acid or (R)-lactic acid.
In animals, L-lactate is constantly produced from pyruvate via the enzyme lactate dehydrogenase (LDH) in a process of fermentationduring normal metabolism and exercise. It does not increase in concentration until the rate of lactate production exceeds the rate of lactate removal, which is governed by a number of factors, including monocarboxylate transporters, concentration and isoform of LDH, and oxidative capacity of tissues. The concentration of blood lactate is usually 12 mmol/L at rest, but can rise to over 20 mmol/L during intense exertion. [citation needed]
In industry, lactic acid fermentation is performed by lactic acid bacteria which convert glucose and sucrose to lactic acid. These bacteria can also grow in the mouth; The acid they produce is responsible for the tooth decay known as caries. [3][4][5][6]
In medicine, lactate is one of the main components of lactated Ringer's solution and Hartmann's solution. These intravenous fluids consist of sodium and potassium cations along with lactate and chloride anions in solution with distilled water, generally in concentrations isotonic with human blood. It is most commonly used for fluid resuscitation after blood loss due to trauma, surgery, or burn injury.
| ITEM |
STANDARD |
| Assay |
Min 80% |
| Density |
1.18-1.20G/ML |
| Stereochemical Purity |
Min 95% |
| Sulphated Ash |
Max 0.1% |
| Chloride |
Max 0.2% |
| Sulphate |
Max 0.25% |
| Iron |
Max 10MG/KG |
| Arsenica |
Max 3MG/KG |
| Lead |
Max 5MG/KG |
| Mercurya |
Max 1MG/KG |
| Heavy metals (as Pb) |
Max 10MG/KG |
| Color |
Max 50APHA |
| L(+)-Lactic acid Basic information |
| Product Name: |
L(+)-Lactic acid |
| Synonyms: |
L-Lactic acid white;2-HYDROXYPIONIC ACID;L-Lactic acid, crystalline, 98.0%+;L-(+)-LACTIC ACID BIOXTRA;L(+)-LACTIC ACID FREE ACID 30% SOLUT;L-(+)-2-HYDROXYPROPANOIC ACID;L-2-HYDROXOPIONIC ACID;SARCOLACTIC ACID |
| CAS: |
79-33-4 |
| MF: |
C3H6O3 |
| MW: |
90.08 |
| EINECS: |
201-196-2 |
| Product Categories: |
Functional Materials;Hydroxycarboxylic Acids (for High-Performance Polymer Research);Food additive and acidulant;Reagent for High-Performance Polymer Research;Intermediates & Fine Chemicals;Pharmaceuticals;Food additives |
| Mol File: |
79-33-4.mol |
| |
| |
| L(+)-Lactic acid Chemical Properties |
| Melting point |
52-54°C |
| alpha |
-13.5 º (c=2.5, 1.5N NaOH) |
| Boiling point |
125 °C |
| density |
1.206 g/mL at 25 °C |
| FEMA |
2611 | LACTIC ACID |
| refractive index |
n20/D 1.427 |
| Fp |
>230 °F |
| storage temp. |
2-8°C |
| solubility |
H2O: 10 mg/mL, clear, colorless |
| pka |
pK at 25°, 3.79 |
| form |
Powder/Solid |
| color |
White |
| optical activity |
[α]20/D 13.5°, c = 2.5 in 1.5 M NaOH |
| Water Solubility |
SOLUBLE |
| Sensitive |
Hygroscopic |
| Merck |
14,5337 |
| JECFA Number |
930 |
| BRN |
1720251 |
| InChIKey |
JVTAAEKCZFNVCJ-REOHCLBHSA-N |
| CAS DataBase Reference |
79-33-4(CAS DataBase Reference) |
| NIST Chemistry Reference |
(s)-2-Hydroxypropanoic acid(79-33-4) |
| EPA Substance Registry System |
L-Lactic acid (79-33-4) |
| Hazard Codes |
Xi,C |
| Risk Statements |
38-41-34-36/37/38-36-35 |
| Safety Statements |
26-39-45-36/37/39-36 |
| RIDADR |
3261 |
| WGK Germany |
1 |
| RTECS |
OD2800000 |
| F |
3-10 |
| TSCA |
Yes |
| HazardClass |
8 |
| PackingGroup |
III |
| HS Code |
29181100 |
| Toxicity |
LD50 intraperitoneal in mouse: 3194mg/kg |
| Provider |
Language |
| ACROS |
English |
| SigmaAldrich |
English |
| ALFA |
English |
| |
| L(+)-Lactic acid Usage And Synthesis |
| |
| L(+)-Lactic acid Preparation Products And Raw materials |
Packing and transportation:
1.Packing:
25kg/ carton or 25kg/bag, or per your requirement.
18mt/20'FCL
2.Storage:
The resin should be stored in a drafty, dry warehouse and away from fire and direct sunlight. It should not be piled up in the open air.
3.Transportation:
During transportation, the product should not be exposed to strong sunlight or rain and should not be transported together with sand, soil, scrap metal, coal or glass. Transportation together with toxic, corrosive and flammable substance is strictly prohibited.
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