General description
D-Glutamic acid is an essential constituent of the bacterial peptidoglycan structure. The conversion of L-glutamate to D-glutamate by glutamate racemase (GR) enzyme is an essential step in the synthesis of peptidoglycan.
There are two forms of glutamic acid found in nature: L-glutamic acid and D-glutamic acid. D-glutamic acid, is not endogenously produced in higher mammals. It is found naturally primarily in the cell walls of certain bacteria. D-glutamate is also present in certain foods e.g., soybeans and also arises from the turnover of the intestinal tract microflora, whose cell walls contain significant D-glutamate. Unlike other D-amino acids, D-glutamate is not oxidized by the D-amino acid oxidases, and therefore this detoxification pathway is not available for handling D-glutamate.
Application
D-glutamic acid is suitable for use in the structure-affinity relationship (SAR)-study of GR (glutamate racemase) enzyme and its inhibitors.
D-Glutamic Acid Powder CAS Number 6893-26-1
| Identification |
| Name |
D(-)-Glutamic acid |
| Synonyms |
D-2-Aminoglutaric acid; (R)-2-Aminopentanedioic acid |
| Molecular Formula |
C5H9NO4 |
| Molecular Weight |
147.13 |
| CAS Registry Number |
6893-26-1 |
| EINECS |
230-000-8 |
| Melting point |
200-202 ºC |
| alpha |
-31.3 º (c=10, 2 N HCl) |
| Water solubility |
7 g/L (20 ºC) |
| D(-)-Glutamic acid Basic information |
| Product Name: |
D(-)-Glutamic acid |
| Synonyms: |
(2R)-2-Aminoglutaric acid;D-α-AMinoglutaric acid;D-1-AMinopropane-1,3-dicarboxylic acid;D(-)-GlutaMic acid, 99+% 25GR;D(-)-GlutaMic acid, 99+% 5GR;(2R)-GlutaMic Acid;NSC 77686;D-2-AMINOPENTANEDIOIC ACID |
| CAS: |
6893-26-1 |
| MF: |
C5H9NO4 |
| MW: |
147.13 |
| EINECS: |
230-000-8 |
| Product Categories: |
Glutamate receptor;amino acid;Amino ACIDS SERIES;Glutamic acid [Glu, E];Amino Acids and Derivatives;alpha-Amino Acids;Amino Acids;Biochemistry;for Resolution of Bases;Optical Resolution;Synthetic Organic Chemistry;Nutritional Supplements;Amino Acids |
| Mol File: |
6893-26-1.mol |
| |
| |
| D(-)-Glutamic acid Chemical Properties |
| Melting point |
200-202 °C (subl.)(lit.) |
| alpha |
-31.3 º (c=10, 2 N HCl) |
| Boiling point |
267.21°C (rough estimate) |
| density |
1.5380 |
| refractive index |
1.4210 (estimate) |
| storage temp. |
Store at RT. |
| pka |
pK1:2.162(+1);pK2:4.272(0);pK3:9.358(-1) (25°C) |
| form |
Powder |
| color |
White to off-white |
| Water Solubility |
7 g/L (20 ºC) |
| Merck |
14,4469 |
| BRN |
1723800 |
| InChIKey |
WHUUTDBJXJRKMK-GSVOUGTGSA-N |
| CAS DataBase Reference |
6893-26-1(CAS DataBase Reference) |
| NIST Chemistry Reference |
D-Glutamic acid(6893-26-1) |
| EPA Substance Registry System |
D-Glutamic acid (6893-26-1) |
| Hazard Codes |
Xi |
| Risk Statements |
36/37/38 |
| Safety Statements |
24/25-36-26 |
| WGK Germany |
3 |
| F |
10 |
| TSCA |
Yes |
| HS Code |
29224200 |
| Provider |
Language |
| D-2-Aminoglutaric acid |
English |
| ACROS |
English |
| SigmaAldrich |
English |
| ALFA |
English |
| |
| D(-)-Glutamic acid Usage And Synthesis |
| Chemical Properties |
White cryst. powder |
| Uses |
D-Glutamic Acid is the unnatural (R)-enantiomer of Glutamic Acid, a non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. Glutamic Acid is also a key molecule in cellular metabolism. |
| Definition |
ChEBI: An optically active form of glutamic acid having D-configuration. |
| Biological Activity |
Excitatory amino acid acting at NMDA receptors; less active than the L-isomer. |
| |
| D(-)-Glutamic acid Preparation Products And Raw materials |
| Raw materials |
DL-Glutamic acid |
| Preparation Products |
5-Hydroxymethylpyrrolidin-2-one |
Hunan JK International Trade Corporation / JK BIO-CHEM CO.,LTD is a professional exporter of food/feed additives and food /feed ingredients in China. With years of development, now we are able to provide the following food additives and food ingredients: thickeners, antioxidants, preservatives, vitamins, sweeteners, proteins, acidulants, nutritional supplements, flavours, coenzyme and so on.
Our food additives and food ingredients, especially our Ascorbic Acid (Vitamin C), Acesulfame-K, Aspartame, Citrates, Dextrose, D-Xylose, Erythorbic Acid, Fumaric Acid, Fructose,Maltodextrin, Malic Acid, Monosodium glutamate, Lactic Acid Potassium Sorbate, Sodium Erythorbate, Sodium Cyclamate, Sodium Saccharin, sodium benzoate, Sodium ascorbate, Sorbic Acid, xanthan Gum, Xylitol, Tartaric Acid, I+G, , Vanillin, Sucralose, Stevia and so on, have been exported to more than 60 countries for our good quality products.
Our staff of sales and technical support is available to help you in selecting the right protection for your application as well as to provide you with samples of our products for evaluation. At High Five, we are committed to providing the highest level of customer service, competitive pricing, speedy delivery and a comprehensive, cutting-edge product offering. Our ultimate goal is your satisfaction.
Packing&Shipping
FAQ
Q1.What's the payment terms?
We could accept T/T, L/C, DP payment terms.
Q2.How about the different index of products in same application?
Specifications can be customized according to your application.
Q3.How about the samples of products?
We can provide free samples under 2Kg(not including freight charge).
Q4.How about the price of products?
Our products are chemical synthesis got from underground brine, which is available for a variety of usage. Our products are high purity with good quality, and the price is based on different specification and quantity.
Q5.What's the shelf life for the cargoes?
Our product's shelf life is 2 years, which is based on dry and ventilated storage.
Q6.What's the package of the cargoes?
20kg/25kg woven bags, within plastic bags, or as customized.
Q7.What's the delivery time?
We usually deliver the cargoes within 10~20 days after receiving customer's payment or original L/C.
Q8.Which documents can we supply?
Commercial Invoice, Packing List, Certificate of Analysis, Certificate of Origin (FORM E), Bill of Loading, ISO etc.
The documents will be sent by Express within 24 hours against your full payment.
Q9.Why do you choose us?
We accept safe and diversified payment terms.
We supply a price trend to ensure clients know marketing information in time. We will take charge of 100% responsibility for
quality issue. We strive to create value for each customer we serve by meeting their unique needs and providing solutions to solve their problems and achieve their objectives.
Audited Supplier 
){kind=link}
){kind=link}