Icariin CAS No. 489-32-7 Icariins

• Certification: ISO
• Assay Method: HPLC, UV
• Application Form: Paste
• Application: Food, Health Care Products, Medicine
• State: Powder
• Extract Source: Organic Curcuma Extract
• Model NO.: food /phar grade
• Store: Dry
• CAS No.: 489-32-7
• M F: C33h40o15
• M G: 676.66
• En No.: 610-440-0
• Transport Package: 25kg/Drum
• Specification: Food grade
• Trademark: JK
• Origin: China
• HS Code: 130239
• Production Capacity: 100mt/Year

Product Description

Epimedium Herb extract

Product Name: Epimedium Herb extract 
Botanical Source: Epimedium alpinum 
Specification: Icariin 5%~ 98% 
Appearance: Yellow to light yellow fine powder

Part Used:	Whole herb

Description

Epimedium, also known as barrenwort, bishop's hat, fairy wings, horny goat eed, or yin yang huo (Chinese: ), is a genus of flowering plants in the family Berberidaceae. The majority of the species are endemic to China, with smaller numbers elsewhere in Asia, and a few in the Mediterranean region.

Epimedium species are deciduous or evergreen hardy perennials. The majority have four-parted "spider-like" flowers in spring.

The species used as a dietary supplement is Epimedium grandiflorum. It contains icariin, which is a weak PDE5 inhibitor in vitro.

Main Function

1. Improve sexual functions of male such as cure impotence, prospermia,barrenness, frigidity etc.

2 . Cure menopause high blood pressure

3. Strengthen internal secretion, anti-aging

4. Anti-cancer

Application Filed

1.In pharmaceutical field

2.In health product field

 

Icariin Basic information

Description References

Product Name:	Icariin
Synonyms:	Icariin 489-32-7;Icariin cas:489-32-7;2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-;4H-1-Benzopyran-4-one,3-[(6-deoxy-α-L-mannopy;ranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-;3-(6-Deoxy-α-L-mannopyranosyloxy)-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;3-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one;Icariln
CAS:	489-32-7
MF:	C33H40O15
MW:	676.66
EINECS:	610-440-0
Product Categories:	Functional Products;Natural Plant Extract;The group of Epimedii;plant extract;Nutritional Ingredients;Plant extracts;Standardized plant extract;Inhibitors;API;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;chemical reagent;pharmaceutical intermediate;Flavones
Mol File:	489-32-7.mol

Icariin Chemical Properties

Melting point	223-225 ºC
alpha	D15 -87.09° (in pyridine)
Boiling point	948.5±65.0 °C(Predicted)
density	1.55
RTECS	DJ2980500
storage temp.	room temp
solubility	DMSO: soluble50mg/mL, clear, colorless to dark yellow
form	Powder
pka	5.90±0.40(Predicted)
color	light yellow to yellow
λmax	350nm(MeOH)(lit.)
Merck	14,3617
InChIKey	TZJALUIVHRYQQB-XLRXWWTNSA-N

Safety Information

Safety Statements	24/25
WGK Germany	3
HS Code	29389090

MSDS Information

 

Icariin Usage And Synthesis

Description	Icariin is one of the major flavonoids of the herb Epimedium, which has long been used in Tranditional Chinese Medicine to treat bone fracture and prevent osteoporosis. Research has shown that icariin should be an effective component for the bone-strengthening activity of the herb Epimedium, and one of the possible mechanisms for this activity is to stimulate the proliferation and enhance the osteogenic differentiation of marrow stromal cells. Icariin is reported to prevent and treat sexual dysfunction related diseases and improve the use of vasoconstriction. Icariin is used to prepare angiotensin converting enzyme inhibitor medicines, which can be used to treat hypertension-complicated coronary diseases.
References	[1] K. M. Chen, B. F. Ge, H. P. Ma, X. Y. Liu, M. H. Bai, Y, Wang (2005) Icariin, a flavonoid from the herb Epimedium enhances the osteogenic differentiation of rat primary bone marrow stromal cells, 60, 939-942 [2] Patent CN 1199647C "Application of icariin in preparation of medicine for preventing and treating sexual dysfunction" [3] Patent CN 104739851 A "New application of icariin, or icariin derivatives or icariin salt"
Chemical Properties	Light yellow to yellow solid
Uses	hepatoprotective

Hunan JK International Trade Corporation / JK BIO-CHEM CO.,LTD is a professional exporter of food/feed additives and food /feed ingredients in China. With years of development, now we are able to provide the following food additives and food ingredients: thickeners, antioxidants, preservatives, vitamins, sweeteners, proteins, acidulants, nutritional supplements, flavours, coenzyme and so on.
Our food additives and food ingredients, especially our Ascorbic Acid (Vitamin C), Acesulfame-K, Aspartame, Citrates, Dextrose, D-Xylose, Erythorbic Acid, Fumaric Acid, Fructose,Maltodextrin, Malic Acid, Monosodium glutamate, Lactic Acid Potassium Sorbate, Sodium Erythorbate, Sodium Cyclamate, Sodium Saccharin, sodium benzoate, Sodium ascorbate, Sorbic Acid, xanthan Gum, Xylitol, Tartaric Acid, I+G, , Vanillin, Sucralose, Stevia and so on, have been exported to more than 60 countries for our good quality products.
Our staff of sales and technical support is available to help you in selecting the right protection for your application as well as to provide you with samples of our products for evaluation. At High Five, we are committed to providing the highest level of customer service, competitive pricing, speedy delivery and a comprehensive, cutting-edge product offering. Our ultimate goal is your satisfaction.





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FAQ
Q1.What's the payment terms?
We could accept T/T, L/C, DP payment terms.

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Specifications can be customized according to your application.

Q3.How about the samples of products?
We can provide free samples under 2Kg(not including freight charge).

Q4.How about the price of products?
Our products are chemical synthesis got from underground brine, which is available for a variety of usage. Our products are high purity with good quality, and the price is based on different specification and quantity.

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Our product's shelf life is 2 years, which is based on dry and ventilated storage.

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20kg/25kg woven bags, within plastic bags, or as customized.

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We usually deliver the cargoes within 10~20 days after receiving customer's payment or original L/C.

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