Benzocaine is a fat soluble surface anaesthetic. Compared with several other local anesthetics such as lidocaine, tetracaine, etc., the strength of effect is small. Owing to its playing role in mucosal, people feel comfort. It is a fat soluble and strong drug, therefore it is easy to combine with the lipid layer of the mucosa or skin, but not easily go through the human body to produce toxic.
Benzocaine is the precursor materials of Ousso imitation, Orthocaine, procaine. At the same time, it is used as a local anesthetic in medicine, and has analgesic, antipruritic effect, mainly used for wounds, ulcers, mucosal surfaces and hemorrhoids narcotic pain and itch. The ointment can also be used for relieving pain and lubrication to nasopharyngeal catheter and the process of PEEP mirror. Temporary relieve pain and itching skin in the wounds of mild burns, sunburn, trauma and insect bites. Ears are used to reduce the pain and itching of acute congestive, concentrated otitis, swimming, and external use. Also it is effective to toothache, sore throat, oral ulcers, hemorrhoids, anal fissure, vulva Sao. As Male Genital Desensitizer make ejaculation slow. Or used as a lubricant for the anesthesia of the catheter and the endoscope.
Application :
Benzocaine is a topical analgesic (meaning it is to be used on the body surface or in the mouth but should not be swallowed) that has a number of different uses in over-the-counter (OTC) medicines. Depending on the dose and form, the active ingredient benzocaine can be used to relieve throat and mouth pain; To alleviate external vaginal itching and burning; To stop pain and itching due to hemorrhoids; Or to relieve minor skin irritations, pain, and itching. Because benzocaine is available in different doses and forms, it is very important to read the Drug Facts label carefully to determine whether the medicine is intended to be used for the symptoms you are experiencing.
Benzocaine can be the only active ingredient in oral treatments that relieve sore throat or address mouth pain caused by cold sores, canker sores, teething, and other issues. It also can be combined with other active ingredients in oral treatments that not only relieve mouth and throat pain, but also protect irritated areas, provide a soothing coating, or relieve dryness.
COA of Benzocaine
Items Tested |
Specification |
Result |
Characters |
A white, crystalline powder or colorless crystals. |
A white crystal. |
Identification |
IR should comply with the Reference Standard spectrum.
UV should comply with the Reference Standard spectrum.
An orange-red precipitate is performed. |
IR complies with the Reference standard spectrum.
UV complies with the Reference standard spectrum.
An orange-red precipitate is performed. |
Melting range |
88 ~92 degree |
89.8-90.2degree |
Loss on Drying |
Not more than 1.0% |
0.22% |
Readily carbonizable Substances |
The resolution has no more color than Matching Fluid A. |
Conform |
Residue on ignition |
Not more than 0.1% |
0.02% |
Heavy metals |
Not more than 0.001% |
Conform |
Chloride |
Conform |
Conform |
Assay (HPLC) |
98.0%-102.0% |
99.96% |
Ordinary Impurities |
≤1% |
Conform |
Reaction |
Conform |
Conform |
PAIN KILLER |
CAS No. |
Benzocaine |
94-09-7 |
Benzocaine HCI |
|
Lidocaine |
137-58-6 |
Lidocaine HCI |
73-78-9 |
Procaine |
59-46-1 |
Procaine HCI |
1951/5/8 |
Prilocaine |
721-50-6 |
Prilocaine HCI |
1786-81-8 |
Tetracaine |
94-24-6 |
Tetracaine HCI |
136-47-0 |
Bupivacaine |
2180-92-9 |
Bupivacaine HCI |
14252-80-3 |
Levobupivacaine Hydrochloride |
27262-48-2 |
Pramoxine HCI |
637-58-1 |
Proparacaine HCI |
5875/6/9 |
Articaine HCI |
23964-57-0 |
Mepivacaine HCl |
1722-62-9 |
Ropivacaine HCI |
132112-35-7/98717-15-8 |
Dibucaine HCI |
85-79-0 |
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