Glycyrrhizine R19,R21
Chinese Name:Glycyrrhizine R19,R21
CAS:1405-86-3
Application:,,.
Loss on Drying:≤8.00%
Residue on Ignition:≤12.00%
Assay:HPLC: 13-20%
Notes:It is a kind of nature sweetener that is 150 times sweeter than sucrose, but without the sourness
| Glycyrrhizic acid Basic information |
| Description References |
| Product Name: |
Glycyrrhizic acid |
| Synonyms: |
carboxy-11-oxo-30- norolean-12-en-3-yl 2-O-β-D-;glucopyranuronosyl-;β-D-Glucopyranosiduronic acid, (3β,20β)-20-;(3beta,20beta)-20-Carboxy-11-oxo-30-norlean-12-en-3-yl-2-O-beta-1- 7-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid;30-Noroleanane, a-D-glucopyranosiduronic acid deriv.;a-D-Glucopyranosiduronic acid, (3b,20b)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-b-D-glucopyranuronosyl-;(20S)-3β-[(2-O-β-D-Glucopyranuronosyl-α-D-glucopyranuronosyl)oxy]-11-oxoolean-12-en-30-oic acid;GLYCYRRHIZIC ACID(P)(CALL) |
| CAS: |
1405-86-3 |
| MF: |
C42H62O16 |
| MW: |
822.93 |
| EINECS: |
215-785-7 |
| Product Categories: |
Tri-Terpenoids;Biochemistry;Disaccharides;Glycosides;Sugars;The group of Liquorice;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors |
| Mol File: |
1405-86-3.mol |
| |
| |
| Glycyrrhizic acid Chemical Properties |
| Melting point |
220°C (rough estimate) |
| alpha |
D17 +46.2° (c = 1.5 in alc) |
| Boiling point |
681.01°C (rough estimate) |
| density |
1.1442 (rough estimate) |
| refractive index |
61 ° (C=1.5, EtOH) |
| pka |
2.76±0.70(Predicted) |
| Merck |
14,4505 |
| InChIKey |
BXFBITNYMHAJGT-KYXJNIQISA-N |
| CAS DataBase Reference |
1405-86-3 |
| EPA Substance Registry System |
Glycyrrhizin (1405-86-3) |
| Safety Statements |
22-24/25 |
| WGK Germany |
3 |
| RTECS |
MD2025000 |
| HS Code |
29389090 |
| Hazardous Substances Data |
1405-86-3(Hazardous Substances Data) |
| Provider |
Language |
| 3-O-(2-O-beta-D-Glucopyranuronosyl-alpha-D-glucopyranuronosyl)-18beta-g lycyrrhetinic acid |
English |
| |
| Glycyrrhizic acid Usage And Synthesis |
| Description |
Glycyrrhizic acid is a kind of anti-inflammatory triterpene glycoside extracted from the licorice root. Inside the body, it can be metabolized to glycyrrhetinic acid which inhibits the 11-beta-hydroxysteroid dehydrogenase and some other enzymes related to the corticosteroid metabolism. Glycyrrhizic acid has various pharmacological effects including suppressing hepatic apoptosis and necrosis, anti-inflammatory and immune regulatory actions, antiviral effects, antineoplastic and anticancer effects. It is the active ingredient of licorice root which is commonly used in the treatment of acute and chronic liver injury, viral hepatitis, hepatic steatosis, liver fibrosis, hepatoma, viral myocarditis and other diseases such as psoriasis or prostate cancer. Glycyrrhizic acid is also widely used as a sweetening and flavoring agent in food. |
| Chemical Properties |
White to off-white powder |
| Uses |
11beta-hydroxysteroid dehydrogenase inhibitor, antiinflammatory, expectorant, antihaemorrhagic, anti-HIV |
| Uses |
Glycyrrhizic acid is a triterpene saponin used in the traditional Chinese medicinal preparation for its anti-inflammatory , antiulcerous and antiallergic effects. |
| Uses |
glycyrrhizic acid is a hydrolyzed glycyrrhizin. It is credited with antiinflammatory and anti-allergenic properties. Studies comparing glycyrrhizin with hydrocortone found glycyrrhizin to be somewhat milder but longer lasting in effectiveness. once the application of hydrocorsone is suspended, the symptoms return. This does not appear to be the case with glycyrrhizin. It does not have side effects and is chemically stable so it can be safely used on a continuing basis. |
| Uses |
Glycyrrhizin is a flavorant and foaming agent derived from the separation of flavonoids found in the whole licorice extract from the licorice root glycyrrhiza glabra. It is 50-100 times as sweet as sugar, is soluble in water, and has a licorice taste. It has good heat stability but prolonged heating can result in some degradation. It is stable within ph 4-9; below ph 4 there could be precipitation. It has foaming and emulsifying properties in water, being used in cocktail mixes and soft drinks. It is used as a flavorant in bacon and imitation whipped products. It is synergistic with sugar, the sweetness being amplified to 100 times that of cane sugar alone. It is used as a sweetener in sugar-free chewing gum and low-fat sugar-free frozen desserts. It is also termed ammoniated glycyrrhizin. Monoammonium glycyrrhizinate is obtained by additional refinement. |
| Definition |
ChEBI: A triterpenoid saponin that is the glucosiduronide derivative of 3beta-hydroxy-11-oxoolean-12-en-30-oic acid. |
| Safety Profile |
Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. Human systemic effects by ingestion: somnolence and changes in the metabolism of phosphorus, When heated to decomposition it emits acrid smoke and irritating fumes. |
| |
| Glycyrrhizic acid Preparation Products And Raw materials |
| Raw materials |
DGL-->VEGETABLEPROTEIN-->IRISH MOSS |
| Preparation Products |
Enoxolone-->Glycyrrhizic acid ammonium salt-->monopotassium and tripotassium glycyrrhi-mate-->Monoglucuronyl glycyrrehetic acid-->LICORICE EXTRACT-->Glucosyl licorice-->licorice root antioxidant-->DISODIUM GLYCYRRHIZATE |
Hunan JK International Trade Corporation / JK BIO-CHEM CO.,LTD is a professional exporter of food/feed additives and food /feed ingredients in China. With years of development, now we are able to provide the following food additives and food ingredients: thickeners, antioxidants, preservatives, vitamins, sweeteners, proteins, acidulants, nutritional supplements, flavours, coenzyme and so on.
Our food additives and food ingredients, especially our Ascorbic Acid (Vitamin C), Acesulfame-K, Aspartame, Citrates, Dextrose, D-Xylose, Erythorbic Acid, Fumaric Acid, Fructose,Maltodextrin, Malic Acid, Monosodium glutamate, Lactic Acid Potassium Sorbate, Sodium Erythorbate, Sodium Cyclamate, Sodium Saccharin, sodium benzoate, Sodium ascorbate, Sorbic Acid, xanthan Gum, Xylitol, Tartaric Acid, I+G, , Vanillin, Sucralose, Stevia and so on, have been exported to more than 60 countries for our good quality products.
Our staff of sales and technical support is available to help you in selecting the right protection for your application as well as to provide you with samples of our products for evaluation. At High Five, we are committed to providing the highest level of customer service, competitive pricing, speedy delivery and a comprehensive, cutting-edge product offering. Our ultimate goal is your satisfaction.
Packing&Shipping
FAQ
Q1.What's the payment terms?
We could accept T/T, L/C, DP payment terms.
Q2.How about the different index of products in same application?
Specifications can be customized according to your application.
Q3.How about the samples of products?
We can provide free samples under 2Kg(not including freight charge).
Q4.How about the price of products?
Our products are chemical synthesis got from underground brine, which is available for a variety of usage. Our products are high purity with good quality, and the price is based on different specification and quantity.
Q5.What's the shelf life for the cargoes?
Our product's shelf life is 2 years, which is based on dry and ventilated storage.
Q6.What's the package of the cargoes?
20kg/25kg woven bags, within plastic bags, or as customized.
Q7.What's the delivery time?
We usually deliver the cargoes within 10~20 days after receiving customer's payment or original L/C.
Q8.Which documents can we supply?
Commercial Invoice, Packing List, Certificate of Analysis, Certificate of Origin (FORM E), Bill of Loading, ISO etc.
The documents will be sent by Express within 24 hours against your full payment.
Q9.Why do you choose us?
We accept safe and diversified payment terms.
We supply a price trend to ensure clients know marketing information in time. We will take charge of 100% responsibility for
quality issue. We strive to create value for each customer we serve by meeting their unique needs and providing solutions to solve their problems and achieve their objectives.
Audited Supplier 
){kind=link}