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Glucosamine Hydrochloride (D-Glucosamine HCl; Glucosamine HCl ) |
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C6H13NO5·HCl MW: 215.63 | \ | ||||||||||||||||||||||||||||||||||||||
CAS No.:66-84-2 | |||||||||||||||||||||||||||||||||||||||
Packing: 25kg/ drum or carton, with 2 layers PE lining. Net weight 25.0kg, Gross weight 27.0kg. Ф33*H38cm Drum or L37*W37*H27cm Carton, or according to customer's requirement. |
D-Glucosamine hydrochloride Basic information |
Product Name: | D-Glucosamine hydrochloride |
Synonyms: | (3R,4R,5S,6R)-3-amino-6;2-DESOXY-2-AMINO-D-GLUCOSE HYDROCHLORIDE;2-AMINO-D-GLUCOSE HYDROCHLORIDE;2-AMINO-2-DEOXY-D-GLUCOPYRANOSE HYDROCHLORIDE;2-AMINO-2-DEOXY-D-GLUCOSE HCL;2-AMINO-2-DEOXY-D-GLUCOSE HYDROCHLORIDE;D-(+)-GLUCOSAMINE HCL;D-GLUCOSAMINE HCL |
CAS: | 66-84-2 |
MF: | C6H14ClNO5 |
MW: | 215.63 |
EINECS: | 200-638-1 |
Product Categories: | Food & Flavor Additives;Amines;Carbohydrates & Derivatives;Biological and chemical;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Anilines, Aromatic Amines and Nitro Compounds;Aminosugars;Biochemistry;Glucose;Sugars;Nutritional Supplements;Dextrins,Sugar & Carbohydrates;Other APIs;Food additives;Inhibitors |
Mol File: | 66-84-2.mol |
D-Glucosamine hydrochloride Chemical Properties |
Melting point | 190-194 °C (dec.)(lit.) |
alpha | 72.5 º (c=2, H2O, 5hrs.) |
refractive index | 72 ° (C=1, H2O) |
storage temp. | Store at RT. |
solubility | H2O: 0.1 g/mL, clear, colorless |
form | crystalline |
Water Solubility | soluble |
Merck | 14,4458 |
BRN | 4157370 |
Stability: | Stable. Incompatible with strong oxidizing agents. Combustible. |
InChIKey | QKPLRMLTKYXDST-LPRXMDNASA-N |
CAS DataBase Reference | 66-84-2(CAS DataBase Reference) |
EPA Substance Registry System | D-Glucose, 2-amino-2-deoxy-, hydrochloride (66-84-2) |
Safety Information |
Hazard Codes | F,Xi,Xn |
Risk Statements | 21-36/38-46-62-63 |
Safety Statements | 24/25-53-36/37-26-25 |
WGK Germany | 2 |
RTECS | LZ6665000 |
F | 3-10 |
Hazard Note | Highly Flammable |
TSCA | Yes |
HS Code | 29329985 |
Hazardous Substances Data | 66-84-2(Hazardous Substances Data) |
D-Glucosamine hydrochloride Usage And Synthesis |
Chemical Properties | white powder |
Uses | Novel application of D-Glucosamine hydrochloride to prepare medical agent for treating vertigo. Found in chitin, in mucoproteins, and in mucopolysaccharides. Antiarthritic. Recent studies show that its chondroprotective activity is related to its antiapoptic properties. |
Uses | glucosamine hydrochloride (glucosamine HCl) is used to adjust the pH of a formulation. It also has anti-static and hair-conditioning properties. |
Purification Methods | Crystallise the hydrochloride froHCl, water, and finally water/EtOH/acne as for galactosamine hydrochloride. [Purchase & Braun Org Synth 26 36 1946, Stacey & Webber Methods in Carbohydrate Chemistry I 228 1962, Academic Press.] The salt has also been purified by dissolving in the minimum volume of boiling H2O (charcoal), filtering and adding a large excess of 95% EtOH (~4 volumes) and stirring vigorously for several hours. Collect the crystals after 4-6hours to give anomer which mutarotates ] D +100o to +72o (equilibrium, c 1, H2O). A large amount of the -anomer stays in solution. This can be precipitated from the filtrate by adding excess Et2O. The mixture of -plus -anomers has [] D +68.8o (c 4.75, H2O, mutarotating to +70.1o)[Leaback Biochemical Preparations 10 118 1963]. Note that if Et2NH is used instead of Et3N, conversion to the -anomer can be complete (see above). [Stacey et al. Methods in Carbohydrate Chemistry I 3061962, Academic Press; Beilstein 4 IV 2018.] |
D-Glucosamine hydrochloride Preparation Products And Raw materials |