Safe Organic Solvents Polysorbate 80 (E433) for used in food and as an emulsifier CAS : 9005-70-3
Basic info:
Tween 85
CAS:9005-70-3
MF:C24H44O6
MW:428.600006103516
EINECS: 500-019-9
form :viscous liquid
EPA Substance Registry System:Sorbitan,
Product Categories: Ester Ether Type (Surfactants);Functional Materials;Nonionic Surfactants;Surfactants;Biochemistry;
Nonionic Surfactants (for Biochemistry);Surfactants (for Biochemistry)
Employ:
Polysorbate 80 is often used in food and other products as an emulsifier.Polysorbate 80 is used as an
emulsifier in the manufacture of medications for parenteral administration, most notably in the popular
anti-arrhythmic amiodarone. It is also part of the adjuvant used in some European and Canadian influenza
vaccines.
Product introduction:
Polysorbate 80 (commercially also known as Tween 80, a registered trademark of ICI Americas, Inc. ) is a
nonionic surfactant and emulsifier derived from polyethoxylated sorbitan and oleic acid, and is often used
in foods. Polysorbate 80 is a viscous, water soluble yellow liquid. The hydrophilic groups in this compound
are polyethers also known as polyoxyethylene groups which are polymers of ethylene oxide. In the
nomenclature of polysorbates, the numeric designation following polysorbate refers to the lipophilic group,
in this case the oleic acid (see polysorbate for more detail).
Polysorbate 80 is used as an emulsifier in foods, particularly in ice cream. Here, polysorbate is added to
up to 0.5% (v/v) concentration and makes the ice cream smoother and easier to handle, as well as
increasing its resistance to melting. Adding this substance prevents milk proteins from completely coating
the fat droplets. This allows them to join together in chains and nets, which hold air in the mixture, and
provide a firmer texture that holds its shape as the ice cream melts.
| Polysorbate 20 Basic information |
| Description References |
| Product Name: |
Polysorbate 20 |
| Synonyms: |
Polisorbate 20- PS 20;Tween 20 (Trademark of ICI America, Inc.);Tween 20 ;Tween 20 1LT;Twain 20;TWEEN(R) 20 Vetec(TM) reagent grade, 40%;ACRYL/BIS 37.5:1 PREMIXED PWD ULTRA PURE;Tween(R) 20 (Polysorbate), NF, Ph Eur |
| CAS: |
9005-64-5 |
| MF: |
C26H50O10 |
| MW: |
522.6692 |
| EINECS: |
500-018-3 |
| Product Categories: |
detergent;Ester Ether Type (Surfactants);Functional Materials;Nonionic Surfactants;Surfactants;Biochemistry;Nonionic Surfactants (for Biochemistry);Surfactants (for Biochemistry);Alphabetical Listings;Flavors and Fragrances;O-P |
| Mol File: |
9005-64-5.mol |
| |
| |
| Polysorbate 20 Chemical Properties |
| Melting point |
98.9 °C (decomp) |
| Boiling point |
100 °C |
| density |
1.11 g/mL at 20 °C |
| vapor pressure |
<1.4 hPa (20 °C) |
| refractive index |
n20/D 1.468(lit.) |
| FEMA |
2915 | POLYSORBATE 20 |
| Fp |
>230 °F |
| storage temp. |
0-6°C |
| solubility |
100 g/L |
| form |
viscous liquid |
| color |
Amber |
| Specific Gravity |
1.090~1.130 (20/20ºC) |
| PH |
6-8 (50g/l, H2O, 20ºC) |
| PH Range |
7 |
| Water Solubility |
100 g/L |
| Hydrophilic-Lipophilic Balance (HLB) |
16.7 |
| Stability: |
Stable. Incompatible with strong oxidizing agents. |
| EPA Substance Registry System |
Polysorbate 20 (9005-64-5) |
| Hazard Codes |
Xi |
| Risk Statements |
22-36/37/38-37/38-41 |
| Safety Statements |
24/25-36/37/39-36-26 |
| WGK Germany |
1 |
| RTECS |
TR7400000 |
| F |
10-23 |
| TSCA |
Yes |
| HS Code |
34021300 |
| Toxicity |
LD50 orally in Rabbit: 38900 mg/kg |
| |
| Polysorbate 20 Usage And Synthesis |
| Description |
Tween 20, whose common commercial names includes Alkest TW 20 and Polysorbate 20, is a mild nonionic surfactant formed by the ethoxylation of sorbitan before the addition of lauric acid which is a medium-chain fatty acid found mainly in coconut oil. It is allowed to be used as the emulsifier, detergent, dispersant, solvent and stabilizer, etc. in a number of fields such as pharmaceutical, chemical, food, textile and other industries due to its stability and relative non-toxicity.
Tween 20 is widely applied in biological techniques and sciences, which can be added to buffers and reagents for immunohistochemistry, such as Western blots and ELISAs, helping to prevent non-specific antibody binding, decrease background staining and enhance reagent spreading. Besides, Tween 20 also has applications in food production as a common food grade additive which are found in many consumables on the market today. It can also be used as a wetting agent in flavored mouth drops such as Ice Drops, in oral or non-gastrointestinal suspensions and in rubber balers in the elastomer industry. |
| References |
https://jk-ingredients.en.made-in-china.com
http://jk-ingredients.en.made-in-china.com |
| Chemical Properties |
Polysorbate 20 is a mixture of laurate partial esters of sorbitol and sorbitol anhydrides condensed with approximately 20 mole of ethylene oxide (C2H4O) for each mole of sorbitol and its mono- and dianhydrides. It has a faint, characteristic odor and a warm, somewhat bitter taste. |
| Chemical Properties |
Yellow liquid |
| Uses |
Pharmaceutic aid (surfactant). |
| Uses |
polysorbate 20 is a solubilizer, emulsifier, viscosity modifier, and stabilizer of essential oils in water. |
| Definition |
ChEBI: A polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by a dodecanoyl group. |
| Preparation |
By condensing the partial esters of sorbitol and its anhydrides with ethylene oxide to effect an oxyethylene copolymerization at the free hydroxyl groups. |
| Brand name |
Tween 20 (ICI Americas). |
| Safety Profile |
Moderately toxic by intravenous route. Mddly toxic by ingestion. A human skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes. |
| |
| Polysorbate 20 Preparation Products And Raw materials |
| Raw materials |
ETHYLENE OXIDE-->Sodium ethoxide |
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