| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Non-Customized |
|
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Quick Detail:
Purity: NLT99.0%
Other Names: D(+)-PHENYLALANINE;D-PHENYLALANINE;
Appearance: White flake crystal
UsageBenzene derivatives/pharmaceutical intermediate/Inhibitors
Packaging: Drum, inner PE bags / outer foil. bags vacuumed packaged
Description:
H-D-PHE-OH is a drug intermediate that is used to treat and prevent osteoporosis, cardiovascular disease, diabetes, atherosclerosis and other diseases.
Applications:
It is a drug intermediate, mainly for the treatment, to prevent osteoporosis, cardiovascular, diabetes, atherosclerosis and other diseases;
It is used as a pharmaceutical intermediates or APIs for the synthesis of drugs such as nateglinide.
Function:
It is a drug intermediate, mainly for the treatment, to prevent osteoporosis, cardiovascular, diabetes, atherosclerosis and other diseases;
It is used as a pharmaceutical intermediates or APIs for the synthesis of drugs such as nateglinide.
Specifications:
|
Items |
Specification |
Results |
|
Appearance |
White flake crystal |
White flake crystal |
|
Assay (HPLC) |
99.0% |
Conform |
|
Melting point(°C) |
273-276 °C(lit.) |
Conform |
| Storage condition | Store at RT. | Conform |
|
Loss on drying (%) |
≤0.5% |
0.25% |
| D-Phenylalanine Basic information |
| Product Name: | D-Phenylalanine |
| Synonyms: | nci-c60195;D-Phenyl-d5-alanine-d3;Endorphenyl;673-06-3;D-Phenylalanine Vetec(TM) reagent grade, >=98%;D-Phe-OH;D-α-Aminohydrocinnamic acid;D-PHENYLALANINE, >=98% (HPLC) |
| CAS: | 673-06-3 |
| MF: | C9H11NO2 |
| MW: | 165.18914 |
| EINECS: | 211-603-5 |
| Product Categories: | Nateglinide intermediate;Inhibitors;Benzene derivatives;Amino ACIDS SERIES;Aromatic Propionic Acids;Phenylalanine [Phe, F];Amino Acids and Derivatives;alpha-Amino Acids;Amino Acids;Biochemistry;Amino Acids;amino acid;chemicals;organic acids;pharmaceutical intermediate;phenlalnine |
| Mol File: | 673-06-3.mol |
| D-Phenylalanine Chemical Properties |
| Melting point | 273-276 °C(lit.) |
| alpha | 33.5 º (c=2, H2O) |
| Boiling point | 293.03°C (rough estimate) |
| density | 1.1603 (rough estimate) |
| refractive index | 34 ° (C=2, H2O) |
| storage temp. | Store at RT. |
| pka | 2.2(at 25ºC) |
| form | Powder |
| color | White to off-white |
| Water Solubility | 27 g/L (20 ºC) |
| Merck | 14,7271 |
| BRN | 2804068 |
| Stability: | Stable. Incompatible with strong oxidizing agents, acids, bases. |
| InChIKey | COLNVLDHVKWLRT-MRVPVSSYSA-N |
| CAS DataBase Reference | 673-06-3(CAS DataBase Reference) |
| EPA Substance Registry System | D-Phenylalanine (673-06-3) |
| Safety Information |
| Hazard Codes | Xi,C |
| Risk Statements | 34 |
| Safety Statements | 24/25-45-36/37/39-27-26 |
| WGK Germany | 3 |
| RTECS | AY7533000 |
| Hazard Note | Irritant |
| TSCA | Yes |
| HS Code | 29224995 |
| Toxicity | TDLo orl-hmn: 500 mg/kg/5W-I:GIT JACTDZ 1(3),124,82 |
| MSDS Information |
| Provider | Language |
|---|---|
| D-alpha-Amino-beta-phenylpropionic acid | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| D-Phenylalanine Usage And Synthesis |
| Description | D-Phenylalanine, also known as D-alpha-Amino-beta-phenylpropionic acid, is a kind of non-proteinogenic amino acid. The biological function of D-phenylalanine remains unclear. However, it has certain anti-depressant, analgesic activities and pharmacological activity at niacin receptor II. The mechanism action of its analgesic activity seems to originate from its inhibition of lin degradation by the carboxypeptidase A. It can also be used as pharmaceutical intermediates that are mainly used to treat, prevent osteoporosis, cardiovascular, diabetes and arterioscleros. |
| Chemical Properties | White crystalline powder |
| Uses | antidepressant |
| Definition | ChEBI: The D-enantiomer of phenylalanine. |
| General Description | Needles or prisms. |
| Air & Water Reactions | Water soluble. Aqueous solutions are weakly acidic. |
| Reactivity Profile | D-alpha-Amino-beta-phenylpropionic acid may be light sensitive. D-alpha-Amino-beta-phenylpropionic acid reacts with strong oxidizing agents, acids and bases. . Act as weak acids in solution. |
| Fire Hazard | Flash point data for D-alpha-Amino-beta-phenylpropionic acid are not available, however D-alpha-Amino-beta-phenylpropionic acid is probably combustible. |
| Safety Profile | Mildly toxic by intraperitoneal route. Human systemic effects by ingestion: nausea, hypermotility, diarrhea. When heated to decomposition it emits toxic fumes of NOx. |
| References | https://jk-ingredients.en.made-in-china.com/ https://jk-ingredients.en.made-in-china.com Christianson, D. W., et al. "Binding of D-phenylalanine and D-tyrosine to carboxypeptidase A. " Journal of Biological Chemistry264.22(1989):12849-53. |
| D-Phenylalanine Preparation Products And Raw materials |
| Raw materials | Acetic anhydride-->DL-Phenylalanine |
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