| Product Name |
Vitamin B5 |
| Part Used |
Herb |
| Appearance |
White Powder |
| Active Ingredient |
d panthenol |
| Specification |
99% |
Panthenol is the alcohol analog of pantothenic acid (vitamin B5), and is thus a provitamin of B5. In organisms it is quickly oxidized to pantothenate [pantothenic acid]. Panthenol is a highly viscous transparent liquid at room temperature, but salts of pantothenic acid (for example sodium pantothenate) are powders (typically white). It is soluble in water, alcohol, propylene glycol, ether and chloroform, and slightly soluble in glycerin.
D-Panthenol is the Provitamin of D-Pantothenic acid(Vitamin B5),which plays a key role in the human intermediary metabolism.Deficiency of Vitamin B5 can result in many dermatological disorders.
D-panthenol is applied in pharmaceutical industry and almost all types of cosmetic preparations.
It cares hair,skin and nails. Role in the skin:
1.deep penetrating moisturizer
2.stimulates epithelization
3.wound healing effect
4.anti-inflammatory effect Role in the hair:
Certificate of Analysis
| Batch Number |
Z20190412001 |
| Production Date |
2019.04.12 |
| Batch Quantity |
80 KGS |
| Item |
Test Standard |
Testing Result |
| Appearance |
Powder |
Complies |
| Color |
white fine powder |
Complies |
| Particle Size |
100% pass 80 mesh |
Complies |
| Oder |
Characteristic |
Complies |
| Taste |
Characteristic |
Complies |
| Loss on Drying |
≤5.0% |
2.20% |
| Residue on Ignition |
≤0.1% |
0.05% |
| Residual acetone |
≤0.1% |
Complies |
| Residual Ethanol |
≤0.5% |
Complies |
| Heave Mentals |
≤10ppm |
Complies |
| Na |
≤0.1% |
<0.1% |
| Pb |
≤3 ppm |
Complies |
| Total Plate |
<1000CFU/g |
Complies |
| Yeast & Mold |
<100 CFU /g |
Complies |
| E. Coli |
Negative |
Complies |
| Salmonella |
Negative |
Complies |
| Conclusion: Conform with USP Standard |
Storage:Closed container. dry & cool. keep away from moisture &strong light
Shelf life:24 Months
Shipping Options as follows
| EMS |
Around 7-10 working days |
| DHL |
Around 3-5 working days |
| Fedex |
Around 4-6 working days |
| TNT |
Around 6-7 working days |
| By Air |
Around 5-7 working days |
| By Sea |
Around 15-30 working days |
| Dexpanthenol Basic information |
| Description References |
| Product Name: |
Dexpanthenol |
| Synonyms: |
4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-(theta)-butanamid;4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-d-(+)-butyramid;Alcopan-250;Bepanthen;Bepanthene;Bepantol;Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-;Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (R)- |
| CAS: |
81-13-0 |
| MF: |
C9H19NO4 |
| MW: |
205.25 |
| EINECS: |
201-327-3 |
| Product Categories: |
Pharmaceutical Intermediates;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;ILOPAN;haircare cosmetics;Inhibitors |
| Mol File: |
81-13-0.mol |
| |
| |
| Dexpanthenol Chemical Properties |
| Melting point |
64~69ºC |
| alpha |
30.5 º (c=5, H2O on anh. sub) |
| Boiling point |
118-120 °C (2.7 mmHg) |
| density |
1.20 g/mL at 20 °C(lit.) |
| refractive index |
1.495-1.502 |
| Fp |
118-120°C/0.02m |
| storage temp. |
?20°C |
| pka |
13.03±0.20(Predicted) |
| form |
Viscous Liquid or Semi Solid |
| color |
Clear colorless to slightly yellow |
| PH |
pH (100g/l,25ºC) : 8.5~10.5 |
| optical activity |
[α]20/D +30±1°, c = 5% in H2O |
| Water Solubility |
soluble |
| Sensitive |
Hygroscopic |
| Merck |
14,2947 |
| BRN |
1724947 |
| InChIKey |
SNPLKNRPJHDVJA-ZETCQYMHSA-N |
| CAS DataBase Reference |
81-13-0(CAS DataBase Reference) |
| NIST Chemistry Reference |
Dexpanthenol(81-13-0) |
| EPA Substance Registry System |
(+)-Panthenol (81-13-0) |
| Hazard Codes |
Xn |
| Risk Statements |
36/37/38-48-41-37/38-20/21/22 |
| Safety Statements |
23-24/25-45-36/37/39-26-22 |
| WGK Germany |
1 |
| RTECS |
ES4316000 |
| F |
3-10 |
| TSCA |
Yes |
| HS Code |
29241990 |
| Hazardous Substances Data |
81-13-0(Hazardous Substances Data) |
| Toxicity |
LD50 oral in mouse: 15gm/kg |
| Provider |
Language |
| (+)-Panthenol |
English |
| SigmaAldrich |
English |
| ACROS |
English |
| ALFA |
English |
| |
| Dexpanthenol Usage And Synthesis |
| Description |
Dexpanthenol belongs to a derivative of pantothenic acid (vitamin B5). It can penetrate the skin and mucous membrane to be quickly oxidized to pantothenic acid. The later one is extremely hygroscopic and binds water effectively. Therefore, Dexpanthenol can be used as a moisturizer. It is added to pharmaceutical and cosmetic products to relieve itching and improve wound healing. In ointments, it can be used for the treatment of sunburns, mild burns, minor skin injuries and disorders. It is also immediately applied after major abdominal surgery to minimize the possibility of paralytic ileus. In addition, it can also be supplemented into the commercial shampoos and hair conditioners to lubricate the hair shaft and give the hair a shiny appearance. The exact mechanism of action of Dexpanthenol is still unclear, perhaps through its enhancing effect on acetylcholine. |
| Chemical Properties |
clear colorless to slightly yellow viscous liquid |
| Uses |
cholinergic |
| Uses |
D-Panthenol is an analogue of pantothenic acid (P190300), a member of the B complex vitamins. D-Panthenol is the biologically active enantiomer of Panthenol. |
| Uses |
immunosuppressant, mitoxantrone analogue less toxic on cardiac tissue antineoplastic |
| Contact allergens |
Pan(to)thenol is the alcohol corresponding to pantothenic acid, of the vitamin B5 group. It is used as a food additive, and in skin and hair products as a conditioning agent. Contact dermatitis and urticaria have been reported. |
| Safety Profile |
Moderately toxic by intravenous route. A skin and eye irritant. When heated to decomposition it emits toxic fumes of NOx. See also AMIDES. |
| Veterinary Drugs and Treatments |
Dexpanthenol has been suggested for use in intestinal atony or distension, postoperative retention of flatus and feces, prophylaxis and treatment of paralytic ileus after abdominal surgery or traumatic injuries, equine colic (not due to mechanical obstruction) and any other condition when there is an impairment of smooth muscle function. Controlled studies are lacking with regard to proving the efficacy of the drug for any of these indications. |
| Purification Methods |
Purify D-panthenol by distillation in vacuo. It is a slightly hygroscopic viscous oil and is soluble in H2O and organic solvents. It is hydrolysed by alkali and strong acid. [Rabin J Am Pharm Assoc (Sci Ed) 37 502 1948, Bonati & Pitré Farmaco Ed Scient 14 43 1959, Beilstein 4 IV 1652.] |
Hunan JK International Trade Corporation / JK BIO-CHEM CO.,LTD is a professional exporter of food/feed additives and food /feed ingredients in China. With years of development, now we are able to provide the following food additives and food ingredients: thickeners, antioxidants, preservatives, vitamins, sweeteners, proteins, acidulants, nutritional supplements, flavours, coenzyme and so on.
Our food additives and food ingredients, especially our Ascorbic Acid (Vitamin C), Acesulfame-K, Aspartame, Citrates, Dextrose, D-Xylose, Erythorbic Acid, Fumaric Acid, Fructose,Maltodextrin, Malic Acid, Monosodium glutamate, Lactic Acid Potassium Sorbate, Sodium Erythorbate, Sodium Cyclamate, Sodium Saccharin, sodium benzoate, Sodium ascorbate, Sorbic Acid, xanthan Gum, Xylitol, Tartaric Acid, I+G, , Vanillin, Sucralose, Stevia and so on, have been exported to more than 60 countries for our good quality products.
Our staff of sales and technical support is available to help you in selecting the right protection for your application as well as to provide you with samples of our products for evaluation. At High Five, we are committed to providing the highest level of customer service, competitive pricing, speedy delivery and a comprehensive, cutting-edge product offering. Our ultimate goal is your satisfaction.
Packing&Shipping
FAQ
Q1.What's the payment terms?
We could accept T/T, L/C, DP payment terms.
Q2.How about the different index of products in same application?
Specifications can be customized according to your application.
Q3.How about the samples of products?
We can provide free samples under 2Kg(not including freight charge).
Q4.How about the price of products?
Our products are chemical synthesis got from underground brine, which is available for a variety of usage. Our products are high purity with good quality, and the price is based on different specification and quantity.
Q5.What's the shelf life for the cargoes?
Our product's shelf life is 2 years, which is based on dry and ventilated storage.
Q6.What's the package of the cargoes?
20kg/25kg woven bags, within plastic bags, or as customized.
Q7.What's the delivery time?
We usually deliver the cargoes within 10~20 days after receiving customer's payment or original L/C.
Q8.Which documents can we supply?
Commercial Invoice, Packing List, Certificate of Analysis, Certificate of Origin (FORM E), Bill of Loading, ISO etc.
The documents will be sent by Express within 24 hours against your full payment.
Q9.Why do you choose us?
We accept safe and diversified payment terms.
We supply a price trend to ensure clients know marketing information in time. We will take charge of 100% responsibility for
quality issue. We strive to create value for each customer we serve by meeting their unique needs and providing solutions to solve their problems and achieve their objectives.
Audited Supplier 
){kind=link}