Ethopabate CAS No. 59-06-3

• Varieties: Parasite Disease Prevention Medicine
• Component: Chemical Synthetic Drugs
• Type: The First Class
• Pharmacodynamic Influential Factors: Combined Medication
• Storage Method: Light Proof
• Store: Dry and Cool Place
• Model NO.: phar
• CAS No.: 59-06-3
• Molecular Formula: C12h15no4
• En No.: 200-414-3
• Delivery: 15days
• Loading Port: Qingdao
• Loading Port 2: Shanghai
• Transport Package: 25kg/Drum
• Specification: BP/USP
• Trademark: JK
• Origin: China
• HS Code: 292429
• Production Capacity: 100mt/Year

Product Description

Basic information
CAS No:59-06-3                                                                              Einecs No.:   200-414-3
Character:white or off-white crystalline powder                     MF:  C12H15NO4
MW: 237.2518                                                                               Purity:99%
Quality Guarantee Period:Two Years Min                                 Grade Standard:enterprise standard
Sample:10-20g Free Sample                                                       

Molecular formula:C12H15NO4
Molecular weight: 237.2518                  

Character : 
this product is white or off-white crystalline powder  ;Tasteless or almost tasteless.This product dissolved in methanol, ethanol and chloroform, and easy dissolved in water.

pharmacology: 
ethoxyamide phenylmethyl ester is a synergistic agent for anti-coccidiasis, and is widely used in clinical practice.The effect and mechanism of acetaminamide phenylmethyl ester is the same as that of sulfa and antibacterial synergistic agents.

indication: 
benzene methyl ester, ethyl amide oxygen to giant chicken, brinell Amy ears ball, and other small intestines ball insect has strong effect, thus make up for the ammonia c Lin on the ball is not strong, the defects of the combined with oxygen amide ethyl benzene methyl soft Amy ears ball is a lack of active faults.In addition, it is compensated for the effective activity of the ammonia prophyrin, thus laying the foundation for the use of the product without the single use.

note:
this product is rarely used alone, and it is used as a premixed agent, such as ammonia prophyrin and sulfaquinoxaline.
 
usage and dosage: 4 ~ 8g for each 1000kg of feed poultry
Quality standard: enterprise standard
Content: ≥ 98.0%
Package:25kg/drum

specification

Items	Specification	Results
Description	White or almost white crystalline powder	white crystalline powder
Identification	Positive reaction	Conform
Meltion Point	147.0~152.0°C	148.1~150.0°C
Residue on ignition	≤0.5%	0.23%
Related Substances	≤2.5%	1.29%
Loss on drying	≤0.5%	0.35%
Assay	98.0%~100.5%	98.3%

 

Ethopabate Basic information

Product Name:	Ethopabate
Synonyms:	4-ACETYLAMINO-2-ETHOXY-BENZOIC ACID METHYL ESTER;METHYL 4-ACETAMIDO-2-ETHOXYBENZOATE;ETHOPABATE;Ethopabate, Vetranal;ETHOPABATE (4-ACETYLAMINO-2-ETHOXY-BENZOIC ACID METHYL ESTER);4-Acetamido-2-ethoxybenzoic acid, methyl ester;Ethopatate;Ethytpatate
CAS:	59-06-3
MF:	C12H15NO4
MW:	237.25
EINECS:	200-414-3
Product Categories:	Aromatic Esters;Amines;Aromatics;Drug Analogues;Intermediates & Fine Chemicals;Pharmaceuticals;NARDIL;animal pharmaceutical
Mol File:	59-06-3.mol

Ethopabate Chemical Properties

Melting point	148-151 °C
Boiling point	426.1±35.0 °C(Predicted)
density	1.180±0.06 g/cm3(Predicted)
storage temp.	0-6°C
pka	14.12±0.70(Predicted)
Merck	13,3781
CAS DataBase Reference	59-06-3(CAS DataBase Reference)
EPA Substance Registry System	Ethopabate (59-06-3)

Safety Information

Hazard Codes	Xn
Risk Statements	22
WGK Germany	3
HS Code	2924296000

MSDS Information

Provider	Language
Ethopabate	English
SigmaAldrich	English

Ethopabate Usage And Synthesis

Chemical Properties	White to Off-White Solid
Uses	A supplementary drug that improves the coccidiostatic effect of nicarbazin and amprolium in order to cure coccidiosis in chickens.
Uses	antidepressant
Clinical Use	Ethopabate is only a narrow anticoccidial spectrum drug against Eimeria acervulina. It has no or only slight activity against E. maxima, E. necatrix, E. tenella or E. brunetti. Today, ethopabate is applied only in combination with amprolium and sulfonamide.
Molecular Interactions	Ethopabate is a 2-substituted PABA derivative (=4-acetamido-2-ethoxybenzoic acid methylester) and functions as a prodrug. Its activity becomes potentiated by pyrimethamine and antagonised by the simultaneous administration of PABA. Thus, the mode of action of ethopabate is similar to that of sulfonamides or sulfones.

Packing&Shipping 


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