• Oleanolic Acid CAS No. 508-02-1 Oleanic Acid
  • Oleanolic Acid CAS No. 508-02-1 Oleanic Acid
  • Oleanolic Acid CAS No. 508-02-1 Oleanic Acid
  • Oleanolic Acid CAS No. 508-02-1 Oleanic Acid
  • Oleanolic Acid CAS No. 508-02-1 Oleanic Acid
  • Oleanolic Acid CAS No. 508-02-1 Oleanic Acid

Oleanolic Acid CAS No. 508-02-1 Oleanic Acid

Certification: BRC, ISO
Assay Method: HPLC, UV
Application Form: Lotion, Suppository, Paste, Tablet
Application: Food, Health Care Products, Medicine
State: Powder
Extract Source: Oleanolic
Samples:
US$ 1/Piece 1 Piece(Min.Order)
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Basic Info.

Model NO.
food grade
Store
Dry and Cool Place
CAS No.
508-02-1
M F
C30h48o3
M G
456.71
En No.
208-081-6
Transport Package
25kg/Drum
Specification
Food grade
Trademark
JK
Origin
China
HS Code
29181990
Production Capacity
100mt/Year

Product Description

Oleanolic Acid
Product Name: Oleanolic Acid,Olean-12-en-28-oic acid, 3-hydroxy-, (3β)-; Oleanol; CARYOPHYLLIN 
Botanical Source: Olea europaea l. 
Part Used: Leaf 
Specification: 98%Oleanolic Acid 
Appearance: Light Yellow Powder

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Description
Oleanolic acid or oleanic acid is a naturally occurring pentacyclic triterpenoid related to betulinic acid. It is widely distributed in food and plants where it exists as a free acid or as an aglycone of triterpenoid saponins.
 
Oleanolic acid can be found in olive oil, Phytolacca americana (American pokeweed), and Syzygium spp, garlic, etc. It was first studied and isolated from several plants, including Olea europaea (leaves, fruit), Rosa woodsii (leaves), Prosopis glandulosa (leaves and twigs), Phoradendron juniperinum (whole plant), Syzygium claviflorum (leaves), Hyptis capitata (whole plant), Mirabilis jalapa[4] and Ternstroemia gymnanthera (aerial part). Other Syzygium species including java apple (Syzygium samarangense) and rose apples contain it.
 
Main Function
1. Reduce liver damage: oleanolic acid as a pentacyclic triterpenoids, CCl4-induced acute and chronic liver injury in rats have a significant protective effect. After treatment, the enlarged mitochondria and dilated rough endoplasmic reticulum were restored. Liver cells can also be acute and chronic liver damage caused by balloon degeneration, necrosis and inflammatory response was significantly reduced. Liver triglyceride accumulation decreased, increased glycogen content.  
 
2. Lower serum alanine aminotransferase activity: oleanolic acid on acute, chronic hepatitis and liver cirrhosis animals were significantly decreased enzyme.  
 
3. Reduce serum r-globulin, and histological observation of the liver is consistent with the reduction of inflammatory response.
 
4. Promote the regeneration of liver cells: oleanolic acid can promote the number of rat liver residual mitotic phase was significantly increased, the regeneration of higher than the control group, suggesting a role in promoting cell regeneration.
 
5. Inhibition of hepatic fibrosis: Oleanolic acid treatment of liver fibrosis in rats, severe and significantly reduced hepatic fibrosis, liver collagen content decreased, suggesting that the role of prevention and treatment of cirrhosis.  
 
6. Chromosome damage has a protective effect on the prevention of experimental atherosclerosis, but also correct protein metabolism disorders.
 
Application Filed
1. Medicine
2. Health Food 


Oleanolic Acid CAS No. 508-02-1 Oleanic Acid



 
Oleanic acid Basic information
Description References
Product Name: Oleanic acid
Synonyms: Astrantigeninc;Caryophyllia;(4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptaMethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid;Oleanolic acid dihydrate, froM HeMsleya chinensis;Oleanolic acid >=97%;Oleanolic Acid Hydrate, 98.0%(T);Oleanolic acid, >=98%;Oleanolic Acid P.E.
CAS: 508-02-1
MF: C30H48O3
MW: 456.71
EINECS: 208-081-6
Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;natural product;Terpenes;Terpenes (Others);Natural Plant Extract;Inhibitors;Pyrazoles;Pentacyclic triterpenes;Tri-Terpenoids;Biochemistry;Anti-proliferative AgentsAsymmetric Synthesis;Complex MoleculesNutrition Research;Isoprenoid/terpenoidCancer Research;Phase I Enzyme Inhibitors;Phase I Enzyme InhibitorsCancer Research;Biochemicals Found in Plants;Cancer Research;Chemopreventive Agents;Chiral Building Blocks;Multidrug Resistance;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
Mol File: 508-02-1.mol
 
 
Oleanic acid Chemical Properties
Melting point  >300 °C(lit.)
alpha  D20 +83.3° (c = 0.6 in chloroform)
Boiling point  502.79°C (rough estimate)
density  1.0261 (rough estimate)
refractive index  1.4940 (estimate)
storage temp.  2-8°C
pka 2.52(at 25ºC)
form  neat
color  light yellow
Merck  14,6827
InChIKey NZQIXFRGWXNLSP-IDYUENATSA-N
CAS DataBase Reference 508-02-1(CAS DataBase Reference)
EPA Substance Registry System Oleanolic acid (508-02-1)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39-60-37
WGK Germany  2
RTECS  RK0177965
TSCA  Yes
HS Code  29181990
 
MSDS Information
Provider Language
3beta-Hydroxyolean-12-en-28-oic acid English
SigmaAldrich English
 
Oleanic acid Usage And Synthesis
Description Oleanolic acid or oleanic acid is a naturally occurring pentacyclic triterpenoid with the formula of C30H48O3. It was found in the non-glyceride fraction of olive pomace oil and is widely distributed in food and plants where it exists as a free acid or as an aglycone precursor for triterpenoid saponins, in which it can be linked to one or more sugar chains. It is biosynthesized from lupane. It can rearrange to the isomer, ursolic acid, or be oxidized to taraxasterol and amyrin. Oleanolic acid and its derivatives possess several promising pharmacological activities, such as hepatoprotective effects, and anti-inflammatory, antioxidant, or anticancer activities.
References 1.https://jk-ingredients.en.made-in-china.com
2.https://www.ncbi.nlm.nih.gov/mesh/68009828
3.http://jk-ingredients.en.made-in-china.com
4.http://jk-ingredients.en.made-in-china.com
Chemical Properties White Solid
Uses A triterpenoid known for its anti-inflammatory properties, is commonly present in several medicinal plants.
Definition ChEBI: A pentacyclic triterpenoid that is olean-12-en-28-oic acid substituted by a beta-hydroxy group at position 3.









Hunan JK International Trade Corporation / JK BIO-CHEM CO.,LTD is a professional exporter of food/feed additives and food /feed ingredients in China. With years of development, now we are able to provide the following food additives and food ingredients: thickeners, antioxidants, preservatives, vitamins, sweeteners, proteins, acidulants, nutritional supplements, flavours, coenzyme and so on.
Our food additives and food ingredients, especially our Ascorbic Acid (Vitamin C), Acesulfame-K, Aspartame, Citrates, Dextrose, D-Xylose, Erythorbic Acid, Fumaric Acid, Fructose,Maltodextrin, Malic Acid, Monosodium glutamate, Lactic Acid Potassium Sorbate, Sodium Erythorbate, Sodium Cyclamate, Sodium Saccharin, sodium benzoate, Sodium ascorbate, Sorbic Acid, xanthan Gum, Xylitol, Tartaric Acid, I+G, , Vanillin, Sucralose, Stevia and so on, have been exported to more than 60 countries for our good quality products.
Our staff of sales and technical support is available to help you in selecting the right protection for your application as well as to provide you with samples of our products for evaluation. At High Five, we are committed to providing the highest level of customer service, competitive pricing, speedy delivery and a comprehensive, cutting-edge product offering. Our ultimate goal is your satisfaction.





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FAQ

Q1.What's the payment terms?
We could accept T/T, L/C, DP payment terms.

Q2.How about the different index of products in same application?
Specifications can be customized according to your application.

Q3.How about the samples of products?
We can provide free samples under 2Kg(not including freight charge).

Q4.How about the price of products?
Our products are chemical synthesis got from underground brine, which is available for a variety of usage. Our products are high purity with good quality, and the price is based on different specification and quantity.

Q5.What's the shelf life for the cargoes?
Our product's shelf life is 2 years, which is based on dry and ventilated storage.

Q6.What's the package of the cargoes?
20kg/25kg woven bags, within plastic bags, or as customized.

Q7.What's the delivery time?
We usually deliver the cargoes within 10~20 days after receiving customer's payment or original L/C.


Q8.Which documents can we supply?
Commercial Invoice, Packing List, Certificate of Analysis, Certificate of Origin (FORM E), Bill of Loading, ISO etc.
The documents will be sent by Express within 24 hours against your full payment.

Q9.Why do you choose us?
We accept safe and diversified payment terms.
We supply a price trend to ensure clients know marketing information in time. We will take charge of 100% responsibility for
quality issue. We strive to create value for each customer we serve by meeting their unique needs and providing solutions to solve their problems and achieve their objectives.









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Gold Member Since 2019

Suppliers with verified business licenses

Rating: 5.0/5
Trading Company
Number of Employees
5
Year of Establishment
2017-12-29